It was discovered that a new blood test detects colon cancer with more than 80% precision, and discards it for 90% of healthy people.
The results were presented in the symposium of gastrointestinal cancers of the American Society of Clinical Oncology 2025 in San Francisco at the end of last month.
They were also published in the Journal of Clinical Oncology.
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In the study, more than 27,000 adults between 45 and 85 years underwent the blood before undergoing a colonoscopy to detect signs of cancer. The participants enrolled between May 2020 and April 2022.
It was discovered that a new blood test detects colon cancer with more than 80% precision, and discards it for 90% of healthy people. (Istock)
The researchers tested the blood samples to obtain “molecular signals of advanced colorectal cell changes” and then compared those results with the colonoscopy findings.
The sensitivity of the test, or its success rate to detect existing colon cancer, was 81.1%, the researchers found.
The specificity of the test, which is the proportion of participants who did not have colon cancer and tested negative for it, was 90.4%.
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“Additional colorectal cancer detection tests are needed that are convenient, safe and easy to complete,” said the principal author Aasma Shaukat, MD, of the Nyu Grossman Faculty of Medicine, in a press release of society American Oncology (disgust).
“Until now, we have only had stool and colonoscopy tests or sigmoidoscopy (stool based). A blood test has the potential to improve colorectal cancer detection rates.”
Colorectal cancer is the fourth most common cancer in the US. And the second most dead type, according to the coastal coastal alliance. (Istock)
Pamela Kunz, MD, from Yale’s Faculty of Medicine, said the experimental blood analysis represents a “new tool in our toolbox” of colorectal cancer detection options.
“The study evaluated blood -based detection for colorectal cancer and can provide a convenient and effective option for the detection of colorectal cancer in the population of average risk,” said Kunz, who did not participate in the study, he declared in The same press release.
“A blood analysis has the potential to improve coloring cancer detection rates.”
Pashtoon Kasi, MD, Medical Director of Gastrointestinal Medical Oncology in the city of Hope Orange County in California, did not participate in the study, but pointed out that this type of blood analysis, also known as “liquid biopsies”, are “revolutionizing attention of cancer “.
“It is a simple blood test that seeks different cancers or tumors components that are spilling in the bloodstream, hence the term ‘liquid biopsy’,” Kasi told Fox News Digital.
Extended detection options are especially important given the tendency that more people are diagnosed with colon cancer under 50 years. (Istock)
Several different types of these blood tests are already reaching clinical practice, the doctor said.
“Some are specific to cancer like this, which will be aimed at the early detection of colon and rectal cancer. Other liquid biopsy tests are what they call early detection tests of multiple cancer (MCED), which means that they can collect multiple cancers only in a blood draw, “he said.
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The doctor said that blood tests should not be used instead of colonoscopias, which remain the “gold standard” of colon cancer detection.
“Colonoscopias can prevent colon cancer through the detection and elimination of polyps, non -cancerous growths in the intestine lining that can become cancerous,” Kasi said.
“Blood analysis is designed to detect cancer, not prevent it.”
If cancer is detected during a blood test, he added additional tests such as a colonoscopy, he added.
“Like most cancers, the early detection of colon cancer generally results in better results,” Kasi said. “Usually, colon cancer is growing slowly, and in its early stages, it can be asymptomatic.”
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At least one third in half of the people do not receive colon cancer exams, studies show, and hope is that blood analysis can help “fill the void,” according to Kasi.
“We know that a colonoscopy generally evokes unpleasant thoughts of intestinal preparation, a liquid and shame diet, so it is not a surprise that blood detection tests offer greater attraction,” he said, describing the blood based test as a “Potential-changing game” in improving detection rates.
“Colorectal cancer is in a particularly steep inclination, so steep that by 2030, it will be the main cause of cancer death for young adults in the United States,” warned an oncologist. (Istock)
Extended detection options are especially important given the tendency that more people are diagnosed with colon cancer under 50 years.
“Colorectal cancer is in a particularly steep inclination, so steep that by 2030, it will be the main cause of cancer death for young adults in the United States,” Kasi warned.
“Blood analysis is designed to detect cancer, not prevent it.”
“It will be imperative to expand research in this area and have diagnostic tests available for a younger demographic group.”
Colorectal cancer is the fourth most common cancer in the US. And the second most dead type, according to the coastal coastal alliance.
Doctors declared that blood tests should not be used instead of colonoscopies, which remain the “gold standard” of colon cancer detection. (Istock)
Looking towards the future, researchers will continue to study the long -term impact of colorectal blood analysis, they said.
“As blood -based tests obtain the approval of regulatory organisms and Medicare and other payers, the tests will be available for clinical use,” said the author of the main study Shaukat to Fox News Digital.
Blood -based tests are options for men and women between 45 and 85 years who have an average risk of colon cancer and due to detection, the doctor said.
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“If you have a history of high risk or other medical condition that puts it at a higher risk of colon cancer, the test is not an option,” he said. “In addition, if the test is positive, it requires a colonoscopy to evaluate colon polyps or colon cancer.”
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The researcher recommends that patients talk to their suppliers about options for the detection of colorectal cancer, such as stool test, blood and colonoscopy analysis, and select the best for them.
The study did not receive any financing, according to the statement.